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Organic Chemistry

Course developer

Prior knowledge

Ķīmi1028, Inorganic Chemistry

Course abstract

Students will obtain knowledge, skills and competence on structure, chemical properties and their alteration influence of cell or environment of bioorganic substances (lipids, membranes, vitamins, carbohydrate, amino acids, proteins, nucleotides, heme, and nucleoproteins) on the base of reaction mechanisms on molecular level, as well as alteration of these properties by mutual interaction that is necessary for further studies of biochemistry, physiology of animals and specialization courses.

Learning outcomes and their assessment

Studies will form the base of fundamental knowledge for studies of biochemistry and further studies of veterinary, e.g., physiology of animals, pharmacology, clinical biochemistry, and professional studies – 1., 2., 3., and 4. Test. The skills to make use of theoretical point of view on structure and common chemical properties of bioorganic compounds to both biochemistry study, and further veterinary studies and in the solving of professional problems, as well as skills to create hypothesis and their possible solutions on the base of empirical data and recent theoretical cognitions – practical and laboratory works. The competence will be developed to students to be able to collect, select, analyze and generalize the information on problems of animals or environment to be created by bioorganic substances and to project path and method to overcome or to prevent it, as well as the competence to explain progress of biochemical reactions on the molecular level both specialists, and clients – colloquium, home works.

Course Content(Calendar)

1. Introduction to the Theoretical Foundations of Bioorganic Compounds' Structure and Reactivity. Properties of Alcohols, Phenols, Ketones, Aldehydes, and Amines / Lab Work 1: Safety Instruction / Properties of Alcohols, Phenols, and Amines (Lectures – 2 h, Laboratory Work – 2 h).
2. Carboxylic Acids, Esters, Hydroxy Acids, Optical Isomers / Test 1 / Homework 1 / Lab Work 2: Carbonyl Group Reactions / Lab Work 3: Carboxylic Acids and Their Derivatives (Lectures – 2 h, Laboratory Work – 2 h).
3. Lipids / Test 2 / Lab Work 4: Properties of Dicarboxylic and Hydroxycarboxylic Acids (Lectures – 2 h, Laboratory Work – 2 h).
4. Carbohydrates I / Homework 2 / Lab Work 5: Fats and Soaps (Lectures – 2 h, Laboratory Work – 2 h).
5. Carbohydrates II / Test 3 / Lab Work 6: Carbohydrates (Lectures – 2 h, Laboratory Work – 2 h).
6. Amino Acids and Proteins / Homework 3 (Lectures – 2 h, Practical Work – 2 h).
7. Nucleic Acids / Laboratory Work Defence (Lectures – 2 h, Practical Work – 2 h).

8. Other Biologically Significant Compounds / Laboratory Work Defence / Test 4 (Lectures – 2 h, Practical Work – 2 h).

Requirements for awarding credit points

At the times specified by the lecturer, the student completes four tests, successfully carries out practical assignments, conducts four laboratory works, submits their reports, and defends the laboratory work at the end of the course.

Description of the organization and tasks of students’ independent work

Preparation of laboratory reports - compilation and systematization of chemical reactions, observation, conclusions and experimental progress.

Criteria for Evaluating Learning Outcomes

Students receive a pass if all laboratory works has been completed, approved, and defended within the designated timeframes, all practical assignments have been completed, and all tests have been successfully written.

Compulsory reading

1. Kreicbergs V. Organiskās un pārtikas ķīmijas pamati. Mācību līdzeklis. Jelgava: LLU, Rīga: Drukātava, 2008. 228 lpp 2. Morozovs A., Jākobsone I., Mekšs P. Pārtikas ķīmija. Rīga: LU Akadēmiskais apgāds, 2008. 208 lpp. 2. Opганическая химия: в вопросах и ответах. Под ред. Ивина Б.А. и Пиотровского Л.Б. Caнкт-Петербург: Наука, 2002. 510 c. 3. McMurry J. Organic chemistry with biological applications. 3rd ed. Stamford : Cengage Learning, c2015. 4. Vollhardt K. P. C., Schore N. E.. Organische Chemie. 4. Aufl. Weinheim: WILEY-VCH, 2005. 1542 S. 5. Dewick P.M. Essentials of Organic Chemistry: for students of pharmacy, medicinal chemistry and biological chemistry. Chichester; Hoboken, N.J.: John Wiley & Sons, 2006. 696 p.

Further reading

1. Klein D.R. Organic Chemistry. 2-nd ed. Hoboken (N.J.): Wiley, 2008. 363 p. 2. Winter A. Organische Chemie für Dummies. Weinheim: Wiley-VCH, 2007. 374 p. 3. Vollhardt K.P.C., Schore N.E. Organic chemistry. In: Structure and Function. 5th ed. New York: W.H.Freeman and company, New York, 2007, p.1254-1366 p.

Periodicals and other sources

1. Bioorganic Chemistry. Published by Elsevier Inc. ISSN: 0045-2068 2. Bioorganic & Medicinal Chemistry. Published by Elsevier Inc. ISSN: 0968-0896 Pilni teksti Science Direct datubāzē

Notes

2nd level professional study “Veterinary Medicine”