Course code InfT2020
Credit points 4.50
Modelling of Biosystems
Total Hours in Course120
Number of hours for lectures16
Number of hours for laboratory classes32
Date of course confirmation12.01.2016
Responsible UnitInstitute of Computer Systems and Data Science
Course developer
Egils Stalidzāns
Dr. sc. ing.
Course abstract
Development of a model and it’s application are important skills in modern biotechnology, medicine and ecology. The course covers the cycle of model development and analysis including the development of model structure as well as determination of model parameters under information insufficiency. Models of different scales – from cellular till population scale are used as case studies.
Learning outcomes and their assessment
• Knowledge about main steps in development of computer models extracting maximal amount of information from available experimental data and literature;
• skills to choose appropriate modelling technology depending on the available amount of information, compare and critically analyse different literature sources;
• competence to apply modelling technologies in order to improve the performance of different bioprocesses replacing experiments by computer simulations, ability to convince the managers of biotechnologically oriented enterprises about the efficiency of modelling approach.
Compulsory reading
1. Selga T. Šūnu bioloģija. Rīga: LU Akadēmiskais apgāds. 2008. 343 lpp.
2. Palsson B. O. Systems Biology: Properties of Reconstructed networks, Cambridge University Press, 2006.
3. Renshaw E. Modelling biological populations in space and time. Cambridge University Press, 1995.
Further reading
1. Szallasi Z., Stelling J., Periwal V. System Modelling in Cell Biology from concepts to nuts and bolts, MIT Press, 2006.