Introduction to Bioinformatics

Total Hours in Course120

Number of hours for lectures16

Number of hours for laboratory classes32

Date of course confirmation18.01.2012

Responsible UnitInstitute of Computer Systems and Data Science

Course developer

prof.

Līga Paura

Dr. agr.

Course abstract

Student gets introduced in basics of bioinformatics, gets acquainted with important bioinformatics data bases and with methods of search and analysis of these date, as well with practical applications of bioinformatics. Course begins with a short introduction into molecular biology, necessary for the understanding for the subject. The basic part of the course is centered on the problems of analysis of biological sequences (protein, RNA and DNA) and the corresponding solutions for these problems, however a brief introduction to analysis of protein structures and phylogenetics is also given.

Learning outcomes and their assessment

• Knowledge depth knowledge and critical understanding about databases and free bioinformatics tools and its application in two and more sequence analysis;
• skills to use internet resources: databases and free bioinformatics tools;
• competence to realize DNA (RNA) and protein sequence analysis by using a bioinformatics software; to interpret the results and to analyze them.

Compulsory reading

1. Claverie J. M., Notredame C. Bioinformatics for Dummies. New York: Wiley, 2003. 452 p.
2. Lesk A. M. Introduction to Bioinformatics. New York: Oxford University press, 2002. 283 p. .
3. Alberts B., Johnson A., Lewis J., Raff M., Roberts K., Walter P. Molecular Biology of the Cell. 4th ed. New York: Garland Science, 2002[tiešsaiste]. Pieejams: http://www.ncbi.nlm.nih.gov/books/NBK21054/ [skatīts 28.12.11] 1463 p.

Atsauksmes