Course code Ķīmi3016

Credit points 2

Organic Chemistry

Total Hours in Course32

Number of hours for lectures16

Number of hours for laboratory classes16

Date of course confirmation12.10.2011

Responsible UnitDepartment of Chemistry

Course developer

author Ķīmijas katedra

Ingmārs Cinkmanis

Dr. sc. ing.

Prior knowledge

Ķīmi1028, Inorganic Chemistry

Course abstract

Students will obtain knowledge, skills and competence on structure, chemical properties and their alteration influence of cell or environment of bioorganic substances (lipids, membranes, vitamins, carbohydrate, amino acids, proteins, nucleotides, heme, and nucleoproteins) on the base of reaction mechanisms on molecular level, as well as alteration of these properties by mutual interaction that is necessary for further studies of biochemistry, physiology of animals and specialization courses.

Learning outcomes and their assessment

Studies will form the base of fundamental knowledge for studies of biochemistry and further studies of veterinary, e.g., physiology of animals, pharmacology, clinical biochemistry, and professional studies – 1., 2., 3., and 4. Test.
The skills to make use of theoretical point of view on structure and common chemical properties of bioorganic compounds to both biochemistry study, and further veterinary studies and in the solving of professional problems, as well as skills to create hypothesis and their possible solutions on the base of empirical data and recent theoretical cognitions - laboratory works. The competence will be developed to students to be able to collect, select, analyze and generalize the information on problems of animals or environment to be created by bioorganic substances and to project path and method to overcome or to prevent it, as well as the competence to explain progress of biochemical reactions on the molecular level both specialists, and clients – colloquium, home works.

Course plan

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9. Lecture: Introduction in to the fundamentals of theoretical structure and reactivity of organic compounds. / 1.Lab. work:: Properties of alcohols, phenols and amines. / 1.Homework
10. Lecture: Metabolites. / 2.Lab. work:: Reactions of carbonyl group. / 1. Test: alcohols, phenols and amines.
11. Lecture: Biologically important heterocyclic compounds. / 3.Lab. work:: Carboxylic acids and their derivatives. / 2. Homework.
12. Lecture: Lipids. / 4.Lab. work: Chemical properties of dicarboxylic and hydroxylic acids. / 2. Test: Properties of biologically important metabolites and heterocyclic compounds.
13. Lecture: Carbohydrates. / 5.Lab. work: Fats, oils and soaps. / 3. Homework.
14. Lecture: Amino acids and proteins. / 6.Lab. work: Carbohydrates. / 3. Test: Properties of lipids and carbohydrates.
15. Lecture: Nucleic acids. / 7.Lab. work: Proteins. / 4. Homework.
16. Lecture: Other biologically important compounds. / 4. Test: Amino acids, proteins and mono- and poly-nucleotides.

Requirements for awarding credit points

Completed exam in the Inorganic Chemistry, 7.laboratory works, and 4 tests have been completed and no lower mark in tests than 4 points.

Description of the organization and tasks of students’ independent work

Preparation of laboratory reports - compilation and systematization of chemical reactions, observation, conclusions and experimental progress.

Criteria for Evaluating Learning Outcomes

It is necessary to write successfully all tests, i.e. no lower mark than 4 points. All laboratory protocols and home works must be checked and completed.

Compulsory reading

1. Kreicbergs V. Organiskās un pārtikas ķīmijas pamati. Mācību līdzeklis. Jelgava: LLU, Rīga: Drukātava, 2008. 228 lpp 2. Morozovs A., Jākobsone I., Mekšs P. Pārtikas ķīmija. Rīga: LU Akadēmiskais apgāds, 2008. 208 lpp. 2. Opганическая химия: в вопросах и ответах. Под ред. Ивина Б.А. и Пиотровского Л.Б. Caнкт-Петербург: Наука, 2002. 510 c. 3. McMurry J. Organic chemistry with biological applications. 3rd ed. Stamford : Cengage Learning, c2015. 4. Vollhardt K. P. C., Schore N. E.. Organische Chemie. 4. Aufl. Weinheim: WILEY-VCH, 2005. 1542 S. 5. Dewick P.M. Essentials of Organic Chemistry: for students of pharmacy, medicinal chemistry and biological chemistry. Chichester; Hoboken, N.J.: John Wiley & Sons, 2006. 696 p.

Further reading

1. Klein D.R. Organic Chemistry. 2-nd ed. Hoboken (N.J.): Wiley, 2008. 363 p. 2. Winter A. Organische Chemie für Dummies. Weinheim: Wiley-VCH, 2007. 374 p. 3. Vollhardt K.P.C., Schore N.E. Organic chemistry. In: Structure and Function. 5th ed. New York: W.H.Freeman and company, New York, 2007, p.1254-1366 p.

Periodicals and other sources

1. Bioorganic Chemistry. Published by Elsevier Inc. ISSN: 0045-2068 2. Bioorganic & Medicinal Chemistry. Published by Elsevier Inc. ISSN: 0968-0896 Pilni teksti Science Direct datubāzē

Notes

2nd level professional study “Veterinary Medicine”